Clinical findings and genetics of the different forms of EB

	EB simplex, EBS Junctional EB, JEB Dystrophic EB, DEB Kindler syndrome
Clinical findings and genetics of the different forms of EB

The clinical differentiation of different forms of EB at birth, or during the first few years of life, is often very difficult. Later, the secondary symptoms of EB are important. Scarring, the involvement of mucous membranes, alopecia, tooth and nail abnormalities, the general health of the patient and the progression of the disorder, all provide important information which may contribute to the correct diagnosis.
The skin layer at which blistering occurs cannot be recognised.

Forms of EB

Epidermolysis bullosa simplex, EBS
Junctional epidermolysis bullosa, JEB
Dystrophic epidermolysis bullosa, DEB
Kindler Syndrome, KS